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First Aired: March 2005 on ABC

Created By: Shonda Rhimes

Starring: Ellen Pompeo as Dr. Meredith Grey, Sandra Oh as Dr. Cristina Yang, Katherine Heigl as Dr. Isobel "Izzie" Stevens, Justin Chambers as Dr. Alex Karev, T.R. Knight as Dr. George O'Malley, Chandra Wilson as Dr. Miranda Bailey, James Pickens Jr. as Dr. Richard Webber, Kate Walsh as Dr. Addison Shepherd, Isaiah Washington as Dr. Preston Burke, and Patrick Dempsey as Dr. Derek Shepherd

Grey's Anatomy TV Show Plot Summary: Comedy, Drama

Tagline: Operations. Relations. Complications.

Plot Outline: A drama centered on the personal and professional lives of five surgical interns and their supervisors.

Reviews of Grey's Anatomy TV Show

Pop Matters Don't let the scrubs and paddles fool you. Grey's Anatomy, which scored the second-biggest drama series premiere audience of the season in its 27 March debut, is a soap, not a hospital procedural. Creator Shonda Rhimes (who penned Britney Spears' Crossroads) makes this clear from the start, as the pilot opens with Meredith Grey (Ellen Pompeo) waking naked but not alone on the den floor of her mother's vacant home. Samantha Bornemann

San Francisco Chronicle What person with a television set doesn't know that young medical interns have it tough? They don't sleep. They're newbies afraid to have people die on them. They are hypercompetitive because they all went to good schools -- save for the one really talented person who struggled at a B-level school but, darn it all, is going to make it. Tim Goodman

New York Magazine Only three episodes into its debut season, Grey’s Anatomy finds itself thinking about brain death. I do not claim that the quality of this thinking, in a dramatic series that seeks to be a sort of “ER goes to the senior prom,” is likely to impress any licensed bioethicists. John Leonard

DVD Town Making a mid-season debut (March 27th, 2005) on the network that had two of television’s biggest breakout hits last year, “Grey’s Anatomy” is the perfect cap to a triumphant return for ABC after several trying years in the TV ratings doldrums. Helped along by the phenomenally popular, “Desperate Housewives” as its lead-in show... Hock Guan Teh

Grey's Anatomy Official Site. Get the inside scoop from the show writers.

Grey's Anatomy Insider Grey's Anatomy quotes, episode guides and views can be found here.